Monoclonal and polyclonal antibodies are available, each with its own advantages and disadvantages. Polyclonal antibodies can bind to many antigen epitopes and are heterogeneous. You can know more about polyclonal antibodies production services online.
Image Source: Google
The specificity of the antibody may be decreased, but it is more likely that the polyclonal antibody will bind to the antigen under a variety of test conditions.
Polyclonal antibody production is a very common procedure in research that involves vertebrate animals. The most common laboratory animal used to produce polyclonal antibodies is the rabbit. There are many benefits to the rabbit over other species. Large blood samples can be collected easily because of the rabbit’s size and easy access to the central auricular and marginal veins.
The rabbit’s excellent response to antigens, its single primary Immunoglobulin G Isotope, as well as a large amount of information on the production and availability of secondary reagents all, contributes to the rabbit’s reputation in polyclonal antibody production.
Research activity is dependent on the production of polyclonal antibodies. Rabbits are still used as a primary species for this purpose. There are many ways to immunize rabbits or produce polyclonal antibodies. They vary based on the immunogenic and adjuvant used.
The production of polyclonal antibodies will be an important research activity. Rabbits will still be the primary species that are used for this purpose. There will be many variations in the methods and schedules used to immunize rabbits or produce polyclonal antibodies. This is dependent on the purpose of the antibody, the adjuvant, and immunogenic.